Mucosal administration of IL-10 enhances oral tolerance in autoimmune encephalomyelitis and diabetes
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چکیده
منابع مشابه
Mucosal administration of IL-10 enhances oral tolerance in autoimmune encephalomyelitis and diabetes.
IL-10 is an immunoregulatory cytokine that can modulate immune processes, inhibiting the expression of inflammatory T(h)1 type responses as well as affecting antigen-presenting cell function. In addition, IL-10 has been shown to be active at mucosal surfaces. In the present study, we examined the role of IL-10 on orally and nasally induced tolerance. Treatment of (PL/J x SJL)F(1) mice with low-...
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ژورنال
عنوان ژورنال: International Immunology
سال: 2001
ISSN: 1460-2377,0953-8178
DOI: 10.1093/intimm/13.6.825